PRODUCT CLASSIFICATION
產品分類Exalpha 凋亡增殖、炎癥、免疫學傳染病學和細胞間結構研究
Exalpha公司簡介
Exalpha有限公司于2000年在馬薩諸塞州雪莉(美國)成立。該公司主要通過開發和生產抗體來支持生命科學領域的研究人員和科學家。
Exalpha公司產品領域
Exalpha公司其領域涉及信號通路、凋亡、增殖、炎癥、免疫學、傳染病學和細胞間結構研究等方面。Exalpha主要產品線包括Proliferation&apoptosis, Enzymes&Proteins, Clinical IHC Markers , GPCRs等多個產品線,可提供給全球的科研實驗室,制藥企業,生物技術和診斷公司,醫院等,目前旗下的代理公司遍布全球。
細胞增殖是生物體的重要生命特征,是生物體生長、發育、繁殖以及遺傳的基礎。監測細胞群的生長對細胞的狀態研究很有必要。科研工作者們經常需要檢測細胞增殖情況,比如驗證抗腫瘤藥物的藥效時,監測細胞增殖及存活情況;研究腫瘤侵襲與轉移模型時,分析細胞轉移或侵襲的路徑;分析創傷的修復或組織的重建時,檢測細胞生長情況等等。檢測細胞增殖及活性變化則可以很好的反映細胞的生長狀況。
細胞增殖的研究方法
細胞增殖的研究方法有很多種,根據檢測原理不同,主要分為DNA合成檢測法、代謝活性檢測法、細胞增殖標志物檢測法等。本文重點介紹DNA合成檢測之Brdu檢測法,傳統DNA合成檢測方法使用胸腺嘧啶核苷(3H-TdR)摻入DNA,然后通過放射自顯影或閃爍計數對DNA進行定量,該方法由于存在放射性物質、實驗周期長、操作繁瑣,且需要昂貴的設備,目前已被BrdU(5-Bromo-2-deoxyuridine,5-溴脫氧尿嘧啶核苷)檢測方法取代,BrdU作為一種胸苷類似物,可選擇性地摻入增殖細胞的DNA中,而且可穩定存在,并帶到子代細胞中,細胞經過固定和變性處理后,可用免疫學方法檢測DNA中BrdU的含量,從而判斷細胞的增殖能力。
Exalpha Biologicals品牌BrdU檢測試劑盒
因組織細胞內無內源性BrdU存在,可利用BrdU相關抗體來檢測和定位摻入活躍增殖細胞新合成DNA的BrdU,Exalpha Biologicals 品牌BrdU檢測試劑盒的優勢在于使用細胞層作為固相,將BrdU試劑摻入微孔板中的細胞,除了對細胞增殖情況進行評估外,還可以從單個培養物中分析細胞數量、形態和細胞抗原等信息。同時Exalpha Biologicals 品牌BrdU檢測試劑盒可通過試劑盒自帶的固定/變性溶液一步完成細胞固定、透化和DNA變性等實驗流程,大大縮短了實驗時間。Exalpha Biologicals 品牌BrdU檢測試劑盒中包含檢測細胞增殖活性所需的所有組分、操作簡便、無放射性、廣泛的樣本適用性,已得到眾多科研工作者的青睞。
Exalpha公司熱銷產品
產品名稱 | 貨號 | 規格 |
BrdU Cell Proliferation Assay Kit | X1327K1 | 200Tests |
chx 10 (Visual system homeobox 2) (NT) Polyclonal Antibody | X1180P | 250ug |
EBNA 3C Polyclonal Antibody | F125P | 250ug |
SURF1 Polyclonal Antibody | X1562P | 100ug |
Bnip3L (IN) (nix) (bcl 2 family) Polyclonal Antibody | X1120P | 100ug |
chx 10 (Visual system homeobox 2) (CT) Polyclonal Antibody | X1179P | 250ug |
Microphthalmia Transcription Factor (MiTF) Monoclonal Antibody | X1405M | 100ug |
EBNA 3A Polyclonal Antibody | F115P | 250ug |
CD5 PE Single-Color Reagent | 0054 | 100Tests |
PTP mu Monoclonal Antibody | P100M | 100ug |
CD117 FITC Single-Color Reagent | 1172 | 100Tests |
Kv1.5 Potassium Channel Polyclonal Antibody | X1501P | 100ug |
N-SMase Activation Associated Factor Antigen Immunoaffinity Purified Polyclonal | X2354P | 100ug |
Chicken anti Glutathione S Transferase (GST), conjugated with HRP | AGST-HRP | 0.1 mg |
CD7 PE Single-Color Reagent | 0074 | 100Tests |
Protein Phosphatase 1 alpha Polyclonal Antibody | P105P | 100ug |
CD2 PE Single-Color Reagent | 0024 | 100Tests |
Kv1.6Potassium Channel Polyclonal Antibody | X1502P | 100ug |
Degenerative Spermatocyte Homolog 2 (DEGS2) Antigen Immunoaffinity Purified Polyclonal | X2356P | 100ug |
CD8 PE Single-Color Reagent | 0084 | 100Tests |
Protein Phosphatase 1 beta Polyclonal Antibody | P110P | 100ug |
CD2 FITC - CD7 PE Bi-Test Reagents (FITC/RPE) | 0027S | 50Tests |
Kv2.1Potassium Channel Polyclonal Antibody | X1503p | 100ug |
Sphingomyelin Phosphodiesterase 3 Antigen Immunoaffinity Purified Polyclonal | X2359P | 100ug |
Chicken anti HA (Hemagglutinin) Epitope | AHA | 0.1 mg |
CD13 PE Single-Color Reagent | 0134 | 100Tests |
Protein Phosphatase 1 beta Polyclonal Antibody | P115P | 100ug |
CD3 PE Single-Color Reagent | 0034 | 100Tests |
Potassium Channel (Kv3.1b ) Polyclonal Antibody | X1504P | 100ug |
Monocarboxylate Transporter 3 (MCT3) Antigen Immunoaffinity Purified Polyclonal | X2361P | 100ug |
Protein Phosphatase 1 gamma 1 Polyclonal Antibody | P120P | 100ug |
CD61 PE Single-Color Reagent | 0614 | 100Tests |
Potassium Channel (Kv4.2 ) Polyclonal Antibody | X1505P | 100ug |
Zinc Finger Protein GLI1 Antigen Immunoaffinity Purified Polyclonal | X2363P | 100ug |
Chicken anti HA (Hemagglutinin) Epitope, conjugated with FITC | AHA-F | 0.1 mg |
CD16 PE Single-Color Reagent | 0164 | 100Tests |
Protein Phosphatase 1 gamma 1 Polyclonal Antibody | P125P | 100ug |
BrdU (bromodeoxyuridine) Monoclonal Antibody | X1028 | 100ug |
Calcium Channel (a1B) Polyclonal Antibody | X1507P | 100ug |
Monocarboxylate Transport 2 Antigen Immunoaffinity Purified Polyclonal | X2368P | 100ug |
Chicken anti HA (Hemagglutinin) Epitope, conjugated with HRP | AHA-HRP | 0.1 mg |
CD18 PE Single-Color Reagent | 0184 | 100Tests |
Protein Phosphatase 1 gamma 2 Polyclonal Antibody | P130P | 100ug |
Muc1 Monoclonal Antibody | X2783M | 100ug |
Voltage-dependent T-type calcium channel subunit alpha-1E Polyclonal Antibody | X1509P | 100ug |
G-Protein Coupled Receptor 94 Antigen Immunoaffinity Purified Polyclonal | X2373P | 100ug |
CD19 PE Single-Color Reagent | 0194 | 100Tests |
Protein Phosphatase 2 A/A Polyclonal Antibody | P140P | 100ug |
CD95 Monoclonal Antibody | X2785M | 100ug |
Calcium Channel (a1G) Polyclonal Antibody | X1510P | 100ug |